Article
Natural polymorphisms of integrase among HIV type 1-infected South African patients.
AIDS research and human retroviruses - 1 Apr 2010
Fish Muhammad Q, Hewer Raymond, Wallis Carole L, Venter Willem D F, Stevens Wendy S, Papathanasopoulos Maria A
Abstract excerpt
An HIV-1 subtype C specific assay was established for integrase genotyping from 51 integrase inhibitor-naive patient plasma samples and 22 antiretroviral drug-naive primary viral isolates from South Africa. Seventy-one of the 73 samples were classified as HIV-1 subtype C and two samples were unique AC and CG recombinants in integrase. Amino acid sequence analysis revealed there were no primary mutations...
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