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Article

Gene-based association tests using GWAS summary statistics and incorporating eQTL.

Scientific reports - 3 Mar 2022

Cao Xuewei, Wang Xuexia, Zhang Shuanglin, Sha Qiuying

Abstract excerpt

Although genome-wide association studies (GWAS) have been successfully applied to a variety of complex diseases and identified many genetic variants underlying complex diseases via single marker tests, there is still a considerable heritability of complex diseases that could not be explained by GWAS. One alternative approach to overcome the missing heritability caused by genetic heterogeneity is gene-based...

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Identifiers

PMID: 35241742
DOI: 10.1038/s41598-022-07465-0
PMCID: PMC8894384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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