Article
Methods for meta-analysis of multiple traits using GWAS summary statistics.
Genetic epidemiology - 1 Mar 2018
Ray Debashree, Boehnke Michael
Abstract excerpt
Genome-wide association studies (GWAS) for complex diseases have focused primarily on single-trait analyses for disease status and disease-related quantitative traits. For example, GWAS on risk factors for coronary artery disease analyze genetic associations of plasma lipids such as total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides (TGs) separately. However, traits are often correlated and a...
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