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Article

How powerful are summary-based methods for identifying expression-trait associations under different genetic architectures?

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2018

Veturi Yogasudha, Ritchie Marylyn D

Abstract excerpt

Transcriptome-wide association studies (TWAS) have recently been employed as an approach that can draw upon the advantages of genome-wide association studies (GWAS) and gene expression studies to identify genes associated with complex traits. Unlike standard GWAS, summary level data suffices for TWAS and offers improved statistical power. Two popular TWAS methods include either (a) imputing the cis genetic...

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PMID: 29218884
PMCID: PMC5785784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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