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Article

Detecting Selection in the HIV-1 Genome during Sexual Transmission Events.

Viruses - 16 Feb 2022

Seifert David, Joos Beda, Braun Dominique L, Oberle Corinna S, Schenkel Corinne D, Kuster Herbert, Grube Christina, Böni Jürg, Yerly Sabine, Aubert Vincent, Klimkait Thomas, Günthard Huldrych F, Beerenwinkel Niko, Metzner Karin J, On Behalf Of The Swiss Hiv Cohort Study

Abstract excerpt

Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles are typically transmitted, and random genetic drift can dilute genetic signals in the recipient virus population. We analyzed 30 transmitter-recipient pairs from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35215999
DOI: 10.3390/v14020406
PMCID: PMC8876189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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