Article
HIV-1 founder variant multiplicity is determined by the infection stage of the source partner
2019-12-04
Abstract excerpt
During sexual transmission, the large genetic diversity of HIV-1 within an individual is frequently reduced to one founder variant that initiates infection 1 . Understanding the drivers of this bottleneck is crucial to develop effective infection control strategies 2 . Genetic characteristics of the potential founder viruses and events in the recipient partner are both known to contribute to this bottleneck, but l...
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Identifiers and source
- Literature Corpus work
- 54360bb7-e6b4-5b88-8111-6b57173fb6b6
- DOI
- 10.1101/19013524