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A transcriptome-wide association study identifies susceptibility genes for Parkinson’s disease

9 Sept 2021

Abstract excerpt

Abstract Genome-wide association study (GWAS) has seen great strides in revealing initial insights into the genetic architecture of Parkinson’s disease (PD). Since GWAS signals often reside in non-coding regions, relatively few of the associations have implicated specific biological mechanisms. Here, we aimed to integrate the GWAS results with large-scale expression quantitative trait loci (eQTL) in 13 brain...

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PMID: 34504106
DOI: 10.1038/s41531-021-00221-7

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