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Article

Deregulated Mitochondrial DNA in Diseases.

DNA and cell biology - 1 Aug 2020

Nguyen Ngoc Ngo Yen, Kim Sung Soo, Jo Yong Hwa

Abstract excerpt

Mitochondria play various important roles in energy production, metabolism, and apoptosis. Mitochondrial dysfunction caused by alterations in mitochondrial DNA (mtDNA) can lead to the initiation and progression of cancers and other diseases. These alterations include mutations and copy number variations. Especially, the mutations in D-loop, MT-ND1, and MT-ND5 affect mitochondrial functions and are widely detected...

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Identifiers

PMID: 31944832
DOI: 10.1089/dna.2019.5220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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