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Article

Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease.

Gut microbes - 1 Jan 2000

Sharma Arunabh, Szymczak Silke, Rühlemann Malte, Freitag-Wolf Sandra, Knecht Carolin, Enderle Janna, Schreiber Stefan, Franke Andre, Lieb Wolfgang, Krawczak Michael, Dempfle Astrid

Abstract excerpt

Dysbiosis of the gut microbiome is a hallmark of inflammatory bowel disease (IBD) and both, IBD risk and microbiome composition, have been found to be associated with genetic variation. Using data from families of IBD patients, we examined the association between genetic and microbiome similarity in a specific IBD context, followed by a genome-wide quantitative trait locus (QTL) linkage analysis of various...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35129060
DOI: 10.1080/19490976.2021.2024415
PMCID: PMC8820822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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