Article
Differences in risk of Crohn's disease in offspring of mothers and fathers with inflammatory bowel disease.
The American journal of gastroenterology - 1 Dec 1997
Akolkar P N, Gulwani-Akolkar B, Heresbach D, Lin X Y, Fisher S, Katz S, Silver J
Abstract excerpt
OBJECTIVE: To determine whether there are any unusual patterns of transmission of susceptibility to inflammatory bowel disease (IBD) within multiplex families. METHODS: Individuals with IBD were recruited for genome-wide screening of susceptibility genes. The extent of familial aggregation and blood relationships in multiplex families were determined by questionnaires given to participants followed up by...
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