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Article

Linkage heterogeneity for the IBD1 locus in Crohn's disease pedigrees by disease onset and severity.

Gastroenterology - 1 Dec 2000

Brant S R, Panhuysen C I, Bailey-Wilson J E, Rohal P M, Lee S, Mann J, Ravenhill G, Kirschner B S, Hanauer S B, Cho J H, Bayless T M

Abstract excerpt

BACKGROUND & AIMS: There is evidence for the IBD1 Crohn's disease (CD) susceptibility locus on chromosome 16 in several but not all populations studied. Genetic and phenotypic heterogeneity may underlie ability to replicate IBD1. We determined if age and severity stratification could identify a clinical subgroup at risk for IBD1. METHODS: Linkage analysis at microsatellites spanning chromosome 16 was performed in...

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Source

Identifiers

PMID: 11113069
DOI: 10.1053/gast.2000.20245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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