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Article

Differences in Clinical Course, Genetics, and the Microbiome Between Familial and Sporadic Inflammatory Bowel Diseases.

Journal of Crohn's & colitis - 27 Apr 2018

Borren Nienke Z, Conway Grace, Garber John J, Khalili Hamed, Budree Shrish, Mallick Himel, Yajnik Vijay, Xavier Ramnik J, Ananthakrishnan Ashwin N

Abstract excerpt

BACKGROUND AND AIM: Family history is the strongest risk factor for developing Crohn's disease [CD] or ulcerative colitis [UC]. We investigated whether the proximity of relationship with the affected relative and concordance for type of inflammatory bowel disease [IBD] modifies the effect of family history on phenotype and disease severity. METHOD: This cross-sectional study included patients with a confirmed...

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Identifiers

PMID: 29145572
DOI: 10.1093/ecco-jcc/jjx154
PMCID: PMC6018966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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