Article

Disease signatures in the gut metagenome of a prospective family cohort of inflammatory bowel disease

2023-12-11

Abstract excerpt

Inflammatory bowel disease (IBD) is associated with dysbiotic microbiomes. However, whether microbiomes of family members of IBD patients harbour microbial disease signatures of IBD is unknown. Here, we generate shotgun metagenomic data of an IBD family cohort and treatment-naive IBD cases, which we combine with published IBD metagenomes, to perform a meta-analysis of IBD-microbiome associations. Our study reveals...

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Literature Corpus work: 89cbbfb5-a5f2-5e56-8282-549267ec814d
DOI: 10.1101/2023.12.10.23299783

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