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Article

Host Genetic and Gut Microbial Signatures in Familial Inflammatory Bowel Disease.

Clinical and translational gastroenterology - 1 Jul 2020

Park Yoo Min, Ha Eunji, Gu Ki-Nam, Shin Ga Young, Lee Chang Kyun, Kim Kwangwoo, Kim Hyo Jong

Abstract excerpt

INTRODUCTION: The family history of inflammatory bowel disease (IBD) has been strongly associated with risk of developing IBD. This study aimed to identify the host genetic and gut microbial signatures in familial IBD. METHODS: Genetic analyses using genome-wide single nucleotide polymorphism genotyping and whole exome sequencing were performed to calculate weighted genetic risk scores from known IBD-associated...

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Identifiers

PMID: 32764209
DOI: 10.14309/ctg.0000000000000213
PMCID: PMC7386341

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