Article
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.
American journal of human genetics - 1 Mar 1999
Hampe J, Schreiber S, Shaw S H, Lau K F, Bridger S, Macpherson A J, Cardon L R, Sakul H, Harris T J, Buckler A, Hall J, Stokkers P, van Deventer S J, Nürnberg P, Mirza M M, Lee J C, Lennard-Jones J E, Mathew C G, Curran M E
Abstract excerpt
Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on the basis of clinical and histologic features: Crohn disease and ulcerative colitis (UC). Previous genomewide searches identified regions harboring susceptibility loci on chromosomes 1, 3, 4, 7, 12, and 16. To expand our understanding of...
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