Association of APOE ε4 with cerebral gray matter volumes in non-demented older adults: The MEMENTO cohort study.

doi:10.1016/j.neuroimage.2022.118966

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Article

Association of APOE ε4 with cerebral gray matter volumes in non-demented older adults: The MEMENTO cohort study.

NeuroImage - 15 Apr 2022

Régy Mélina, Dugravot Aline, Sabia Séverine, Fayosse Aurore, Mangin Jean-Francois, Chupin Marie, Fischer Clara, Bouteloup Vincent, Dufouil Carole, Chêne Geneviève, Paquet Claire, Hanseeuw Bernard, Singh-Manoux Archana, Dumurgier Julien

Abstract excerpt

Data on 2,045 non-demented individuals with memory complaints were drawn from the Memento cohort study to examine the association between Apolipoprotein E ε4 allele (APOE4) and regional brain gray matter volumes. Linear regression was used to examine the association of APOE4 and measures of regional gray matter volumes in cross-sectional analysis and change therein using longitudinal analyses based on two brain...

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