Article
Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment.
Archives of neurology - 1 Jun 2005
Fleisher Adam, Grundman Michael, Jack Clifford R, Petersen Ronald C, Taylor Curtis, Kim Hyun T, Schiller Denise H B, Bagwell Victor, Sencakova Drahomira, Weiner Myron F, DeCarli Charles, DeKosky Steven T, van Dyck Christopher H, Thal Leon J
Abstract excerpt
BACKGROUND: Subjects with mild cognitive impairment (MCI) have been shown to have reduced hippocampal volumes relative to normal elderly control subjects. The presence of the apolipoprotein E epsilon4 (APOE*E4) allele has been associated with greater hippocampal atrophy in women than in men with...
Topics
- Aged
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Atrophy
- Cognition Disorders
- Female
- Hippocampus
- Humans
- Male
- Sex Characteristics