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Article

APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age.

Journal of Alzheimer's disease : JAD - 1 Jan 2012

Bunce David, Anstey Kaarin J, Cherbuin Nicolas, Gautam Prapti, Sachdev Perminder, Easteal Simon

Abstract excerpt

The apolipoprotein E (APOE) ε4 allele is a risk factor for the neuropathological decline accompanying Alzheimer's disease (AD) while, conversely, the ε2 allele offers protection. One of the brain structures exhibiting the earliest changes associated with the disease is the entorhinal cortex. We therefore investigated the volumes of the entorhinal cortex and other structures in the medial temporal lobe including...

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Source

Identifiers

PMID: 22475794
DOI: 10.3233/JAD-2012-112126

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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