Article
Absence of a significant interaction of two common NOS1 and 5-HTT polymorphisms on sensorimotor gating in humans.
Physiological research - 31 Dec 2021
Rovný R, Marko M, Minárik G, Riečanský I
Abstract excerpt
The neurotransmitter serotonin has been critically implicated in the pathogenesis of several mental disorders. The serotonin transporter (5-HTT) is a key regulator of serotonergic neurotransmission and its genetic variability is associated with increased risk of psychopathology. One well known polymorphic locus in the 5-HTT gene affecting its expression is a tandem repeat in the promoter region (5-HTTLPR). It has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
