Article
Association between genetic variability of neuronal nitric oxide synthase and sensorimotor gating in humans.
Nitric oxide : biology and chemistry - 1 Nov 2018
Rovný Rastislav, Marko Martin, Katina Stanislav, Murínová Jana, Roháriková Veronika, Cimrová Barbora, Repiská Gabriela, Minárik Gabriel, Riečanský Igor
Abstract excerpt
Research increasingly suggests that nitric oxide (NO) plays a role in the pathogenesis of schizophrenia. One important line of evidence comes from genetic studies, which have repeatedly detected an association between the neuronal isoform of nitric oxide synthase (nNOS or NOS1) and schizophrenia. However, the pathogenetic pathways linking nNOS, NO, and the disorder remain poorly understood. A deficit in...
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