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Article

The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating.

Biological psychiatry - 15 Jun 2016

Roussos Panos, Giakoumaki Stella G, Zouraraki Chrysoula, Fullard John F, Karagiorga Vasiliki-Eirini, Tsapakis Eva-Maria, Petraki Zoe, Siever Larry J, Lencz Todd, Malhotra Anil, Spanaki Cleanthe, Bitsios Panos

Abstract excerpt

BACKGROUND: Prepulse inhibition (PPI) of the startle reflex has been suggested as a candidate endophenotype for schizophrenia research, as it shows high heritability and has been found deficient in schizophrenia spectrum disorders. The objectives of the study were to 1) identify common genetic variants associated with baseline startle and PPI; 2) estimate the single nucleotide polymorphism heritability; and 3)...

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Identifiers

PMID: 26212897
DOI: 10.1016/j.biopsych.2015.06.019

Genes

CALN1
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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