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Article

Sensorimotor gating and D2 receptor signalling: evidence from a molecular genetic approach.

The international journal of neuropsychopharmacology - 1 Nov 2012

Völter Christoph, Riedel Michael, Wöstmann Nicola, Aichert Désirée S, Lobo Sarah, Costa Anna, Schmechtig Anne, Collier David A, Hartmann Annette M, Giegling Ina, Möller Hans-Jürgen, Quednow Boris B, Rujescu Dan, Kumari Veena, Ettinger Ulrich

Abstract excerpt

Converging evidence from pharmacological investigations, genetic association studies and schizophrenia research indicates an important influence of the dopamine system on sensorimotor gating as measured by prepulse inhibition (PPI) of the acoustic startle response. In particular, D2 receptor agonists have been shown to disrupt PPI in humans and rodents. In the present study, we investigated the associations of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 22244514
DOI: 10.1017/S1461145711001787

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Sensorimotor gating and D2 receptor signalling: evidence from a molecular genetic approach.PMID 22244514Read ↗

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