Article
Neuronal Nitric Oxide Synthase (nNOS, NOS1) rs693534 and rs7977109 Variants and Risk for Migraine.
Headache - 1 Oct 2015
García-Martín Elena, Martínez Carmen, Serrador Mercedes, Alonso-Navarro Hortensia, Navacerrada Francisco, García-Albea Esteban, Agúndez José A G, Jiménez-Jiménez Félix Javier
Abstract excerpt
BACKGROUND/OBJECTIVES: Many biochemical, pharmacological, neuropathological, and experimental data suggest a possible role of nitric oxide in the pathogenesis of migraine. We investigated the possible association between functional single nucleotide polymorphisms (SNPs) in the neuronal nitric oxide synthase gene (NOS1 or nNOS; chromosome 12q24.22) and the risk for migraine. METHODS: We studied the frequency of...
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