Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles.

doi:10.1126/sciimmunol.abf5314

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Article

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles.

Science immunology - 28 Jan 2022

Tan Hyon-Xhi, Juno Jennifer A, Esterbauer Robyn, Kelly Hannah G, Wragg Kathleen M, Konstandopoulos Penny, Alcantara Sheilajen, Alvarado Carolina, Jones Robert, Starkey Graham, Wang Boa Zhong, Yoshino Osamu, Tiang Thomas, Grayson M Lindsay, Opdam Helen, D'Costa Rohit, Vago Angela, Mackay Laura K, Gordon Claire L, Masopust David, Groom Joanna R, Kent Stephen J, Wheatley Adam K

Abstract excerpt

Recent studies have established that memory B cells, largely thought to be circulatory in the blood, can take up long-term residency in inflamed tissues, analogous to widely described tissue-resident T cells. The dynamics of recruitment and retention of memory B cells to tissues and their immunological purpose remains unclear. Here, we characterized tissue-resident memory B cells (BRM) that are stably maintained...

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PMID: 35089815
DOI: 10.1126/sciimmunol.abf5314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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