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Article

Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections.

Frontiers in immunology - 1 Jan 2021

Humphries Duncan C, O'Connor Richard A, Larocque Daniel, Chabaud-Riou Martine, Dhaliwal Kevin, Pavot Vincent

Abstract excerpt

There is increasing evidence that lung-resident memory T and B cells play a critical role in protecting against respiratory reinfection. With a unique transcriptional and phenotypic profile, resident memory lymphocytes are maintained in a quiescent state, constantly surveying the lung for microbial intruders. Upon reactivation with cognate antigen, these cells provide rapid effector function to enhance immunity...

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Identifiers

PMID: 34603321
DOI: 10.3389/fimmu.2021.738955
PMCID: PMC8485048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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