Article
The phenotypic and functional study of tissue B cells in respiratory system provided important information for diseases and development of vaccines.
Journal of cellular and molecular medicine - 1 Mar 2021
Fan Li, Wu Qiongli, Kang Shuangpeng, Yang Binyan, Wu Changyou
Abstract excerpt
The field of tissue-resident B cells has received increasing attention, yet the feature of tissue B cells in respiratory system is unclear. Here, we first show that non-circulating B cells obtained from nasal, trachea and lung tissues are numerically and phenotypically distinct from their circulating counterparts. Analysis of single cell transcriptome sequence identified multiple differentially expressed genes...
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