Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lung niches for the generation and maintenance of tissue-resident memory T cells.

Mucosal immunology - 1 May 2014

Turner D L, Bickham K L, Thome J J, Kim C Y, D'Ovidio F, Wherry E J, Farber D L

Abstract excerpt

The extent to which tissue-specific viral infections generate memory T cells specifically adapted to and maintained within the target infection site is unknown. Here, we show that respiratory virus-specific memory T cells in mice and humans are generated and maintained in compartmentalized niches in lungs, distinct from populations in lymphoid tissue or circulation. Using a polyclonal mouse model of influenza...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to Immunologic Memory
Share to Immunophenotyping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Lymphoid Tissue

Share to Orthomyxoviridae Infections

Share to T-Cell Antigen Receptor Specificity

Share to T-Lymphocyte Subsets

Source

Open in PubMed Open full text

Identifiers

PMID: 24064670
DOI: 10.1038/mi.2013.67
PMCID: PMC3965651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lung niches for the generation and maintenance of tissue-resident memory T cells.PMID 24064670Read ↗

Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunctionSemantic proximity Read ↗

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.Semantic proximity Read ↗

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles.Semantic proximity Read ↗

Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in miceSemantic proximity Read ↗

Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections.Semantic proximity Read ↗

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells.Semantic proximity Read ↗

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites.Semantic proximity Read ↗

Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study.Semantic proximity Read ↗

Unique properties of tissue-resident memory T cells in the lungs: implications for COVID-19 and other respiratory diseasesSemantic proximity Read ↗

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells.Semantic proximity Read ↗

Axes of heterogeneity in human tissue-resident memory T cells.Semantic proximity Read ↗

Rapid reactivation of extralymphoid CD4 T cells during secondary infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.