Article
Genetic prediction of ICU hospitalization and mortality in COVID-19 patients using artificial neural networks.
Journal of cellular and molecular medicine - 1 Mar 2022
Asteris Panagiotis G, Gavriilaki Eleni, Touloumenidou Tasoula, Koravou Evaggelia-Evdoxia, Koutra Maria, Papayanni Penelope Georgia, Pouleres Alexandros, Karali Vassiliki, Lemonis Minas E, Mamou Anna, Skentou Athanasia D, Papalexandri Apostolia, Varelas Christos, Chatzopoulou Fani, Chatzidimitriou Maria, Chatzidimitriou Dimitrios, Veleni Anastasia, Rapti Evdoxia, Kioumis Ioannis, Kaimakamis Evaggelos, Bitzani Milly, Boumpas Dimitrios, Tsantes Argyris, Sotiropoulos Damianos, Papadopoulou Anastasia, Kalantzis Ioannis G, Vallianatou Lydia A, Armaghani Danial J, Cavaleri Liborio, Gandomi Amir H, Hajihassani Mohsen, Hasanipanah Mahdi, Koopialipoor Mohammadreza, Lourenço Paulo B, Samui Pijush, Zhou Jian, Sakellari Ioanna, Valsami Serena, Politou Marianna, Kokoris Styliani, Anagnostopoulos Achilles
Abstract excerpt
There is an unmet need of models for early prediction of morbidity and mortality of Coronavirus disease-19 (COVID-19). We aimed to a) identify complement-related genetic variants associated with the clinical outcomes of ICU hospitalization and death, b) develop an artificial neural network (ANN) predicting these outcomes and c) validate whether complement-related variants are associated with an impaired...
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