Article

Upregulation of CD55 complement regulator in distinct PBMC subpopulations of COVID-19 patients is associated with suppression of interferon responses

2022-10-07

Abstract excerpt

Complement activation has been verified in COVID-19 patients by both increased serum levels of complement factors C3a and C5b-9 and increased complement deposition at the tissue levels. Complement regulatory proteins (CRPs) CD55, CD46, CD59 and CR1 act to control complement overactivation and eliminate complement deposition and cell lysis. The aim of the study was to investigate the expression of CRPs in COVID-19...

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Literature Corpus work: 9d71d4f8-6481-57ef-aeb3-8f5a0120cd04
DOI: 10.1101/2022.10.07.510750

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