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Article

Combination of WFDC2, CHI3L1, and KRT19 in Plasma Defines a Clinically Useful Molecular Phenotype Associated with Prognosis in Critically Ill COVID-19 Patients.

Journal of clinical immunology - 1 Feb 2023

Ebihara Takeshi, Matsubara Tsunehiro, Togami Yuki, Matsumoto Hisatake, Tachino Jotaro, Matsuura Hiroshi, Kojima Takashi, Sugihara Fuminori, Seno Shigeto, Okuzaki Daisuke, Hirata Haruhiko, Ogura Hiroshi

Abstract excerpt

BACKGROUND: COVID-19 is now a common disease, but its pathogenesis remains unknown. Blood circulating proteins reflect host defenses against COVID-19. We investigated whether evaluation of longitudinal blood proteomics for COVID-19 and merging with clinical information would allow elucidation of its pathogenesis and develop a useful clinical phenotype. METHODS: To achieve the first goal (determining key...

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Identifiers

PMID: 36331721
DOI: 10.1007/s10875-022-01386-3
PMCID: PMC9638294

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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