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Article

Smad2: a candidate gene for the murine autoimmune diabetes locus Idd21.1.

The Journal of clinical endocrinology and metabolism - 1 Dec 2011

Hook Sarah M, Phipps-Green Amanda J, Faiz Fathimath, McNoe Les, McKinney Cushla, Hollis-Moffatt Jade E, Merriman Tony R

Abstract excerpt

CONTEXT: Congenic NOD.ABH(D18Mit8-D18Mit214) mice, which contain greater than 12.8 Mb of DNA encompassing Idd21.1 from diabetes-resistant Biozzi/ABH mice, have a lower frequency of diabetes compared with the parental nonobese diabetic (NOD) strain, possibly due to reduced pathogenicity of β-islet-infiltrating immune cells. OBJECTIVE: The objective of the study was to identify an Idd21.1 candidate gene. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21976717
DOI: 10.1210/jc.2011-0463

Genes

SMAD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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