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Article

Accuracy of mutational signature software on correlated signatures.

Scientific reports - 10 Jan 2022

Wu Yang, Chua Ellora Hui Zhen, Ng Alvin Wei Tian, Boot Arnoud, Rozen Steven G

Abstract excerpt

Mutational signatures are characteristic patterns of mutations generated by exogenous mutagens or by endogenous mutational processes. Mutational signatures are important for research into DNA damage and repair, aging, cancer biology, genetic toxicology, and epidemiology. Unsupervised learning can infer mutational signatures from the somatic mutations in large numbers of tumors, and separating correlated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35013428
DOI: 10.1038/s41598-021-04207-6
PMCID: PMC8748538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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