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Article

Apolipoprotein E: implications for AD neurobiology, epidemiology and risk assessment.

Neurobiology of aging - 1 May 2011

Schipper Hyman M

Abstract excerpt

Alzheimer disease (AD) is a common and devastating dementing illness for which there is no effective neuroprotective therapy or cure. The presence of the apolipoprotein E (apoE) ε4 allele is a well-established genetic modifier (risk factor) of sporadic AD. In this review, we provide an update on the implications of apoE for the neurobiology and epidemiology of AD. Moreover, recent evidence is adduced indicating...

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Source

Identifiers

PMID: 19482376
DOI: 10.1016/j.neurobiolaging.2009.04.021

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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