Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis.

Biomolecules - 25 Nov 2021

Gajić Dragica, Despotović Sanja, Koprivica Ivan, Miljković Đorđe, Saksida Tamara

Abstract excerpt

Ethyl pyruvate (EP) has profound anti-inflammatory and immunomodulatory properties. Here, its effects were determined on experimental autoimmune myocarditis (EAM) induced in mice by heart-specific myosin-alpha heavy chain peptide immunization. EP was applied intraperitoneally, daily, starting with the immunization. Severity of EAM was determined by histological assessment of immune cell infiltrates into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Autoimmune Diseases
Share to Culture Media

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymph Nodes

Share to Myocarditis

Share to Pyruvates

Share to Th1 Cells

Share to Th17 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 34944410
DOI: 10.3390/biom11121768
PMCID: PMC8698267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis.PMID 34944410Read ↗

Empagliflozin attenuates inflammation levels in autoimmune myocarditis through the STAT3 pathway and macrophage phenotype transformation.Semantic proximity Read ↗

Experimental autoimmune myocarditis in A/J mice is an interleukin-4-dependent disease with a Th2 phenotype.Semantic proximity Read ↗

ROCK inhibitor Y-27632 down-regulates Il-1β expression in mice with experimental autoimmune myocarditisSemantic proximity Read ↗

Effects of atorvastatin on the Th1/Th2 polarization of ongoing experimental autoimmune myocarditis in Lewis rats.Semantic proximity Read ↗

STAT4 silencing underlies a novel inhibitory role of microRNA-141-3p in inflammation response of mice with experimental autoimmune myocarditisSemantic proximity Read ↗

Myosin-primed tolerogenic dendritic cells ameliorate experimental autoimmune myocarditis.Semantic proximity Read ↗

Recombinant murine interleukin-12 facilitates induction of cardiac myosin-specific type 1 helper T cells in rats.Semantic proximity Read ↗

Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model.Semantic proximity Read ↗

Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway.Semantic proximity Read ↗

A locus on chromosome 1 promotes susceptibility of experimental autoimmune myocarditis and lymphocyte cell death.Semantic proximity Read ↗

Development of an improved animal model of experimental autoimmune myositis.Semantic proximity Read ↗

Increase in cholinergic modulation with pyridostigmine induces anti-inflammatory cell recruitment soon after acute myocardial infarction in rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.