Article

ROCK inhibitor Y-27632 down-regulates Il-1β expression in mice with experimental autoimmune myocarditis

2023-09-26

Abstract excerpt

<title>Abstract</title> <p>Autoimmune myocarditis is a limited or diffuse inflammation of the myocardium brought on by dysfunction in the normal function of cellular and humoral immunity of the body. Mouse models of experimental autoimmune myocarditis (EAM) were constructed using peptide MyHC-α614–629. After secondary immunization, the mice were given intraperitoneal injection of the Rho kinase (ROCK) inhibitor Y...

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Literature Corpus work: 50e7d126-86f1-5d0e-a5fc-ef9faf8e8c90
DOI: 10.21203/rs.3.rs-3324490/v1

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