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Article

Increase in cholinergic modulation with pyridostigmine induces anti-inflammatory cell recruitment soon after acute myocardial infarction in rats.

American journal of physiology. Regulatory, integrative and comparative physiology - 15 Apr 2016

Rocha Juraci Aparecida, Ribeiro Susan Pereira, França Cristiane Miranda, Coelho Otávio, Alves Gisele, Lacchini Silvia, Kallás Esper Georges, Irigoyen Maria Cláudia, Consolim-Colombo Fernanda M

Abstract excerpt

We tested the hypothesis that an increase in the anti-inflammatory cholinergic pathway, when induced by pyridostigmine (PY), may modulate subtypes of lymphocytes (CD4+, CD8+, FOXP3+) and macrophages (M1/M2) soon after myocardial infarction (MI) in rats. Wistar rats, randomly allocated to receive PY (40 mg·kg(-1)·day(-1)) in drinking water or to stay without treatment, were followed for 4 days and then were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26791829
DOI: 10.1152/ajpregu.00328.2015
PMCID: PMC4867407

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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