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Article

A locus on chromosome 1 promotes susceptibility of experimental autoimmune myocarditis and lymphocyte cell death.

Clinical immunology (Orlando, Fla.) - 1 Jan 2009

Ligons Davinna L, Guler Mehmet L, Li Haiyan S, Rose Noel R

Abstract excerpt

We previously identified by linkage analysis a region on chromosome 1 (Eam1) that confers susceptibility to experimental autoimmune myocarditis (EAM). To evaluate the role of Eam1, we created a congenic mouse strain, carrying the susceptible Eam1 locus of A.SW on the resistant B10.S background (B10.A-Eam1 congenic) and analyzed three outcomes: 1) the incidence and severity of EAM, 2) the susceptibility of lymph...

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Identifiers

PMID: 18951849
DOI: 10.1016/j.clim.2008.06.015
PMCID: PMC2640841

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Source receipt: pubmed, retrieved 7 Sept 2026.

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