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Article

Development of an improved animal model of experimental autoimmune myositis.

International journal of clinical and experimental pathology - 1 Jan 2015

Kang Juan, Zhang Hong-Ya, Feng Guo-Dong, Feng Dong-Yun, Jia Hong-Ge

Abstract excerpt

Multiple animal models of experimental autoimmune myositis (EAM) have been developed. However, these models vary greatly in the severity of disease and reproducibility. The goal of this study was to test whether vaccination twice with increased dose of rat myosin and pertussis toxin (PT) could induce EAM with severer disease in mice. BALB/c mice were injected with 1 mg rat myosin in 50% complete Freund's adjuvant...

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Identifiers

PMID: 26823763
PMCID: PMC4713549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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