Article
Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model.
PloS one - 1 Jan 2016
Blázquez Rebeca, Sánchez-Margallo Francisco Miguel, Crisóstomo Verónica, Báez Claudia, Maestre Juan, Álvarez Verónica, Casado Javier G
Abstract excerpt
INTRODUCTION: The intrapericardial delivery has been defined as an efficient method for pharmacological agent delivery. Here we hypothesize that intrapericardial administration of cardiosphere-derived cells (CDCs) may have an immunomodulatory effect providing an optimal microenvironment for promoting cardiac repair. To our knowledge, this is the first report studying the effects of CDCs for myocardial repair...
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