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Senescent Cells in Cancer: Wanted or Unwanted Citizens

26 Nov 2021

Abstract excerpt

Over recent decades, the field of cellular senescence has attracted considerable attention due to its association with aging, the development of age-related diseases and cancer. Senescent cells are unable to proliferate, as the pathways responsible for initiating the cell cycle are irreversibly inhibited. Nevertheless, senescent cells accumulate in tissues and develop a pro-inflammatory secretome, known as the...

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PMID: 34943822
DOI: 10.3390/cells10123315

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