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Senescence and senolysis in cancer: The latest findings

19 Apr 2024

Abstract excerpt

Aging is a life phenomenon that occurs in most living organisms and is a major risk factor for many diseases, including cancer. Cellular senescence is a cellular trait induced by various genomic and epigenetic stresses. Senescent cells are characterized by irreversible cell growth arrest and excessive secretion of inflammatory cytokines (senescence-associated secretory phenotypes, SASP). Chronic tissue...

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PMID: 38641866
DOI: 10.1111/cas.16184

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