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Article

Cell senescence, the senescence-associated secretory phenotype, and cancers.

PLoS biology - 1 Sept 2023

Langhi Prata Larissa G P, Tchkonia Tamar, Kirkland James L

Abstract excerpt

Cellular senescence is a cell fate caused by multiple stresses. A 2008 article in PLOS Biology reported a senescence-associated secretory phenotype that can promote inflammation and cancer, eventually enabling the development of senolytic drugs.

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Topics

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Share to Advanced biosensing and bioanalysis techniques
Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Neoplasms

Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

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Share to Telomeres, Telomerase, and Senescence

Source

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Identifiers

PMID: 37733806
DOI: 10.1371/journal.pbio.3002326
PMCID: PMC10547493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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