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The Contribution of Physiological and Accelerated Aging to Cancer Progression Through Senescence-Induced Inflammation

21 Sept 2021

Abstract excerpt

Senescent cells are found to accumulate in aged individuals, as well as in cancer patients that receive chemotherapeutic treatment. Although originally believed to halt cancer progression due to their characteristic growth arrest, senescent cells remain metabolically active and secrete a combination of inflammatory agents, growth factors and proteases, collectively known as the senescence-associated secretory...

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PMID: 34621683
DOI: 10.3389/fonc.2021.747822

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