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Article

Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank.

British journal of cancer - 1 Mar 2022

Zhang Xiaomeng, Li Xue, He Yazhou, Law Philip J, Farrington Susan M, Campbell Harry, Tomlinson Ian P M, Houlston Richard S, Dunlop Malcolm G, Timofeeva Maria, Theodoratou Evropi

Abstract excerpt

BACKGROUND: Associations between colorectal cancer (CRC) and other health outcomes have been reported, but these may be subject to biases, or due to limitations of observational studies. METHODS: We set out to determine whether genetic predisposition to CRC is also associated with the risk of other phenotypes. Under the phenome-wide association study (PheWAS) and tree-structured phenotypic model (TreeWAS), we...

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Identifiers

PMID: 34912076
DOI: 10.1038/s41416-021-01655-9
PMCID: PMC8888597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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