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Article

Prediction of colorectal cancer risk based on profiling with common genetic variants.

International journal of cancer - 15 Dec 2020

Li Xue, Timofeeva Maria, Spiliopoulou Athina, McKeigue Paul, He Yazhou, Zhang Xiaomeng, Svinti Victoria, Campbell Harry, Houlston Richard S, Tomlinson Ian P M, Farrington Susan M, Dunlop Malcolm G, Theodoratou Evropi

Abstract excerpt

Increasing numbers of common genetic variants associated with colorectal cancer (CRC) have been identified. Our study aimed to determine whether risk prediction based on common genetic variants might enable stratification for CRC risk. Meta-analysis of 11 genome-wide association studies comprising 16 871 cases and 26 328 controls was performed to capture CRC susceptibility variants. Genetic prediction models with...

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PMID: 32638365
DOI: 10.1002/ijc.33191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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