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Article

Ability of known colorectal cancer susceptibility SNPs to predict colorectal cancer risk: A cohort study within the UK Biobank.

PloS one - 1 Jan 2021

Gafni Aviv, Dite Gillian S, Spaeth Tuff Erika, Allman Richard, Hopper John L

Abstract excerpt

Colorectal cancer risk stratification is crucial to improve screening and risk-reducing recommendations, and consequently do better than a one-size-fits-all screening regimen. Current screening guidelines in the UK, USA and Australia focus solely on family history and age for risk prediction, even though the vast majority of the population do not have any family history. We investigated adding a polygenic risk...

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Identifiers

PMID: 34525106
DOI: 10.1371/journal.pone.0251469
PMCID: PMC8443076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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