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Colorectal cancer risk stratification using a polygenic risk score in symptomatic patients presenting to primary care – a UK Biobank retrospective cohort study

2023-12-09

Abstract excerpt

Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide. Accurate cancer risk stratification approaches could increase rates of early CRC diagnosis, improve health outcomes for patients and reduce pressure on diagnostic services. The faecal immunochemical test (FIT) for blood in stool is widely used in primary care to identify symptomatic patients with likely CRC. However, there is a 6–16% noncomp...

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Literature Corpus work
1ebfd8ad-a8ac-525e-9dea-9899c90cdf7e
DOI
10.1101/2023.12.08.23299717
Open publication

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