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Article

MEKK3-TGFβ crosstalk regulates inward arterial remodeling.

Proceedings of the National Academy of Sciences of the United States of America - 21 Dec 2021

Deng Hanqiang, Xu Yanying, Hu Xiaoyue, Zhuang Zhen W, Chang Yuzhou, Wang Yewei, Ntokou Aglaia, Schwartz Martin A, Su Bing, Simons Michael

Abstract excerpt

Arterial remodeling is an important adaptive mechanism that maintains normal fluid shear stress in a variety of physiologic and pathologic conditions. Inward remodeling, a process that leads to reduction in arterial diameter, plays a critical role in progression of such common diseases as hypertension and atherosclerosis. Yet, despite its pathogenic importance, molecular mechanisms controlling inward remodeling...

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Identifiers

PMID: 34911761
DOI: 10.1073/pnas.2112625118
PMCID: PMC8713777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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