Article

MEKK3-TGFβ crosstalk regulates inward arterial remodeling

2021-08-19

Abstract excerpt

Arterial remodeling is an important adaptive mechanism that maintains normal fluid shear stress in a variety of physiologic and pathologic conditions. Inward remodeling, a process that leads to reduction in arterial diameter, plays a critical role in progression of such common diseases as hypertension and atherosclerosis. Yet despite its pathogenic importance, molecular mechanisms controlling inward remodeling rem...

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Literature Corpus work: 55250c3a-fb6c-5dcf-8ec4-64182cbcf195
DOI: 10.1101/2021.08.19.456893

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