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Article

Global molecular alterations involving recurrence or progression of pediatric brain tumors.

Neoplasia (New York, N.Y.) - 1 Jan 2022

Chen Fengju, Chandrashekar Darshan S, Scheurer Michael E, Varambally Sooryanarayana, Creighton Chad J

Abstract excerpt

BACKGROUND: We aimed to identify molecular changes in recurrent or progressive pediatric brain tumors, as compared to the corresponding initial tumors from the same patients, using genomic, transcriptomic, and proteomic data from a unique and large cohort of 55 patients and 63 recurrent or progressive tumors from the Children's Brain Tumor Tissue Consortium, representing various histologic types. METHODS: We...

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Identifiers

PMID: 34864569
DOI: 10.1016/j.neo.2021.11.014
PMCID: PMC8649620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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